What is solitary bone metastasis?

Background: The term ‘solitary bone metastasis’ is defined in the present study as a single bone metastasis originating from a primary cancer without visceral organ metastasis.

Are there different types of bone metastasis?

Types of bone metastasis Osteolytic, characterized by destruction of normal bone, present in multiple myeloma (MM), renal cell carcinoma, melanoma, non-small cell lung cancer, non-hodgkin lymphoma, thyroid cancer or langerhans-cell histiocytosis. The great majority of BC produces osteolytic metastases.

Is Plasmacytosis a cancer?

Plasmacytoma is a very rare form of blood cancer that’s similar to multiple myeloma. There are two types of plasmacytomas — solitary plasmacytoma of bone (SPB) and extramedullary plasmacytoma (EMP).

What is a single metastasis?

Cancer can spread from the original location by traveling through the lymph system or the bloodstream. A person may have a single metastatic tumor, which would be called a metastasis. If there is more than one metastatic tumor, it is called metastases (the plural of metastasis).

What does metastasis look like on MRI?

On MRI, metastases are usually iso- or hypointense on T1, hyperintense on T2, and exhibit avid enhancement [Figure 1]. Some metastases, such as melanoma, are T1 hyperintense due to the paramagnetic effects of melanin [Figure 3].

What is osteolytic and osteoblastic?

Bone metastases are generally characterized as osteolytic, leading to bone destruction, or osteosclerotic (osteoblastic), leading to new bone formation 3. Breast cancer metastases are usually osteolytic, and prostate cancer metastases are usually osteoblastic.

What causes bone metastasis?

Bone metastasis occurs when cancer cells spread from their original site to a bone. Nearly all types of cancer can spread (metastasize) to the bones. But some types of cancer are particularly likely to spread to bone, including breast cancer and prostate cancer.

What causes plasmacytosis?

There are many causes of reactive bone marrow plasmacytosis including infection, malignancy, inflammation, Castleman’s disease, iron deficiency, megaloblastic anaemia, haemolytic anaemia, diabetes mellitus, cirrhosis,5 and streptokinase treatment.

Are plasmacytomas painful?

Symptoms. Spinal plasmacytomas may cause dull, aching pain as they destroy normal bone. If a vertebra is sufficiently weakened by the plasmacytoma, a painful compression fracture may result. Spinal plasmacytomas may cause other symptoms that vary depending on the tumor’s size and location.