Guidelines

Which insulin is used for diabetic ketoacidosis?

Which insulin is used for diabetic ketoacidosis?

Insulin lispro (Humalog)

Does insulin cause diabetic ketoacidosis?

Diabetic ketoacidosis is usually triggered by: An illness. An infection or other illness can cause your body to produce higher levels of certain hormones, such as adrenaline or cortisol. Unfortunately, these hormones counter the effect of insulin — sometimes triggering an episode of diabetic ketoacidosis.

How does insulin prevent ketoacidosis?

Insulin allows our cells to absorb and utilize these sugars. DKA occurs when the body cannot produce sufficient insulin to absorb glucose and must rely on a secondary energy source. When this happens, hormones are released to break down fats for fuel. As the fat is broken down, acids called ketones are released.

When do you give insulin for DKA?

The half-life of regular insulin is less than 10 minutes. Therefore, to avoid relapse of diabetic ketoacidosis, the first subcutaneous dose of regular insulin should be given at least one hour before intravenous insulin is discontinued.

How much insulin do you give for ketoacidosis?

A mix of 24 units of regular insulin in 60 mL of isotonic sodium chloride solution usually is infused at a rate of 15 mL/h (6 U/h) until the blood glucose level drops to less than 180 mg/dL; the rate of infusion then decreases to 5-7.5 mL/h (2-3 U/h) until the ketoacidotic state abates.

Why does diabetic ketoacidosis occur?

DKA develops when your body doesn’t have enough insulin to allow blood sugar into your cells for use as energy. Instead, your liver breaks down fat for fuel, a process that produces acids called ketones. When too many ketones are produced too fast, they can build up to dangerous levels in your body.

What is the most appropriate treatment for DKA?

Insulin reverses the processes that cause diabetic ketoacidosis. In addition to fluids and electrolytes, you’ll receive insulin therapy — usually through a vein.

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