Does Charcot-Marie-Tooth affect the brain?

CMT causes damage to the peripheral nerves, which carry signals from the brain and spinal cord to the muscles and relay sensations, such as pain and touch, to the brain and spinal cord from the rest of the body.

Is Charcot-Marie-Tooth a disability?

Medically Qualifying Under A Disability Listing: CMT is a form of peripheral neuropathy, meaning it affects the nerves and muscles in the arms, legs, hands, and feet. The Social Security Administration (SSA) has a standard disability listing for this type of neurological disorder.

Is Charcot Marie Tooth painful?

Because CMT causes damage to sensory nerve fibers (axons), people with CMT can feel tingling and burning sensations in the hands and feet, usually causing only mild discomfort but sometimes causing pain. The sense of touch is diminished, as is the ability to sense changes in temperature.

Does Charcot Marie Tooth affect the brain?

Can CMT be passed from father to son?

Therefore, X-linked diseases usually affect males more severely than females, because males have only one X chromosome. X-linked diseases (like CMTX) cannot be passed from father to son. Autosomal inheritance means the mutation occurs on a chromosome other than the X or Y.

Can CMT affect your heart?

As far as we know, CMT does not affect the heart. CMT also does not affect the autonomic nervous system (ANS). The ANS is a part of the peripheral nervous system that regulates the functions of our internal organs, such as the heart, stomach and intestines.

Should people with CMT have children?

Generally speaking, there is no reason why you shouldn’t have children of your own. However, there are issues you need to consider. If you or your partner has CMT, you have up to a one in two chance of passing the condition onto your child.

What is the pathophysiology of Charcot–Marie–Tooth disease?

Charcot–Marie–Tooth disease is caused by genetic mutations that cause defects in neuronal proteins. Nerve signals are conducted by an axon with a myelin sheath wrapped around it.

What is Charcot-Marie-Tooth disease (CHT)?

Charcot-Marie-Tooth disease is also called hereditary motor and sensory neuropathy. Charcot-Marie-Tooth disease results in smaller, weaker muscles.

What are the complications of Charcot-Marie-Tooth disease?

Complications of Charcot-Marie-Tooth disease vary in severity from person to person. Foot abnormalities and difficulty walking are usually the most serious problems. Muscles may get weaker, and you may injure areas of the body that experience decreased sensation.