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Is serum creatinine the same as creatinine clearance?

Is serum creatinine the same as creatinine clearance?

This is an important question. There is a difference between looking at creatinine in your bloodstream (called “serum creatinine”) and looking at creatinine in your urine (called “creatinine clearance”). These are two different lab tests. Serum creatinine is part of a routine lab report; creatinine clearance is not.

Why is creatinine clearance better than serum creatinine?

As it is not easy to measure the GFR directly, the serum creatinine concentration is often used to assess renal function. Creatinine clearance provides a more accurate assessment and can be calculated from the serum creatinine or more exactly from the results of a 24-hour urine collection.

What is serum creatinine clearance?

Creatinine clearance is a measure of how well the kidneys filter creatinine out of the bloodstream for excretion in urine. Creatinine clearance is usually determined from a measurement of creatinine in a 24-hour urine sample and from a serum sample taken during the same time period.

What is creatinine clearance test used for?

The purpose of a creatinine clearance test is to assess kidney function. In particular, creatinine clearance is used to determine the estimated glomerular filtration rate (eGFR), which describes how well the kidneys are filtering the blood.

What is the difference between creatine and creatinine?

The main difference between creatine and creatinine is that creatine is a naturally occurring amino acid in vertebrates which helps to supply energy to muscles and nerve cells whereas creatinine is a biological waste formed by the metabolism of creatine and excreted from the body in urine.

What is clearance test?

The creatinine clearance test checks your kidney function by looking at the amount of creatinine in your urine and blood. Creatinine is a waste product that’s typically filtered out of your blood by your kidneys. Abnormal levels of creatinine could be a sign of kidney failure.

What happens when serum creatinine is high?

High serum creatinine levels in the blood indicate that the kidneys aren’t functioning properly. Your serum creatinine levels may be slightly elevated or higher than normal due to: a blocked urinary tract. a high-protein diet.

What causes high serum creatinine?

Possible causes of a higher creatinine level include: kidney damage or kidney failure. kidney infection. reduced blood flow to the kidneys.

What is relation between creatine and creatinine?

Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass). Creatinine and its clearance are the main measures of kidney function. You have to be careful not to overload your kidneys with high creatine consumption.

What is the difference between creatinine clearance and GFR?

Creatinine clearance ( CrCl ) is an estimate of Glomerular Filtration Rate ( GFR ); however, CrCl is slightly higher than true GFR because creatinine is secreted by the proximal tubule (in addition to being filtered by the glomerulus). The additional proximal tubule secretion falsely elevates the CrCl estimate of GFR .

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