Is Xigris still on the market?
Eli Lilly and Company announces withdrawal of its Xigris(R) [drotrecogin alfa (activated)] product in all markets following results of the PROWESS-SHOCK study, which showed the study did not meet the primary endpoint of a statistically significant reduction in 28-day all-cause mortality in patients with septic shock.
How much did Xigris cost?
Xigris cost approximately $8,000 per treatment course.
Is Xigris an antibiotic?
Xigris (drotrecogin alfa) contains no antibacterial preservatives; the intravenous solution should be prepared immediately after reconstitution of the Xigris (drotrecogin alfa) in the vial(s).
What was Vioxx used for?
Vioxx is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). Vioxx is also related to the nonselective NSAIDs , such as ibuprofen and naproxen. Vioxx is a prescription medicine used to relieve signs and symptoms of arthritis, acute pain in adults, and painful menstrual cycles.
How do you say drotrecogin alfa?
Pronunciation : droe-tre-KOE-gin AL-fa Latest prescription information about Drotrecogin Alfa.
How does drotrecogin alfa works and its indications for use?
Drotrecogin alfa is similar to a natural protein produced by the body (activated protein C). In patients with severe, life-threatening bacterial infections, drotrecogin alfa decreases inflammation and the formation of blood clots in blood vessels. It also increases the breakdown of blood clots.
What is drotrecogin used for?
Drotrecogin alfa (activated) is a new therapeutic agent approved for reduction of mortality in adult patients with severe sepsis. Currently no other treatments are available or pending approval for severe sepsis. Drotrecogin alfa (activated) is a re-combinant form of human activated protein C.
How many died from Vioxx?
By the time Vioxx is withdrawn from market, an estimated 20 million Americans have taken the drug. Research later published in the medical journal Lancet estimates that 88,000 Americans had heart attacks from taking Vioxx, and 38,000 of them died.