What is the tonicity of 0.3% sodium chloride?
Monitoring of serum sodium is particularly important for hypotonic fluids. Potassium Chloride 0.3% & Sodium Chloride 0.9% Solution for Infusion has a tonicity of 388 mOsm/l (approx.)
Is 3% sodium chloride isotonic?
Sodium toxicity is almost always related to how fast a sodium deficit is corrected. Too rapid an administration may result in an increase in serum osmolality, resulting in CNS hemorrhage….3% HYPERTONIC Sodium Chloride (NaCl)

Concentration | mmol/L Na | Osmolarity (mosm/L) |
---|---|---|
0.9% NaCl (“Isotonic”, “Normal Saline”) | 154 | 310 |
3% Hypertonic NaCl | 513 | 1,025 |
What is the tonicity of NaCl?
The osmolarity of normal saline, 9 grams NaCl dissolved in water to a total volume of one liter, is a close approximation to the osmolarity of NaCl in blood (about 290 mOsm/L). Thus, normal saline is almost isotonic to blood plasma.
What is the osmolarity of NaCl?
A 1 mol/L NaCl solution has an osmolarity of 2 osmol/L. A mole of NaCl dissociates fully in water to yield two moles of particles: Na+ ions and Cl- ions. Each mole of NaCl becomes two osmoles in solution.
Is 3 NaCl hypertonic or hypotonic?
3% Sodium Chloride Injection is hypertonic with an osmolarity of 1,027 mOsmol/L.

Is 3 NaCl hypotonic hypertonic or isotonic?
Hypertonic Solutions. Hypertonic solutions have a higher concentration of dissolved particles than blood. An example of hypertonic IV solution is 3% Normal Saline (3% NaCl).
Is 3% sodium chloride hypertonic?
3% and 5% Sodium Chloride Injection, USP is hypertonic with an osmolarity of 1027 mOsmol/L and 1711 mOsmol/L, respectively. Administration of hypertonic solutions may cause venous damage and thus should be administered through a large vein, for rapid dilution.
What is sodium chloride 3%?
Three percent sodium chloride (3% NaCl) is a hyperosmolar agent that can be lifesaving for patients with severe hyponatremic encephalopathy, traumatic brain injury, and cerebral edema.
Is 0.2% NaCl isotonic hypotonic or hypertonic?
hypotonic
Both 0.2 NaCl and 0.45 NaCl are hypotonic fluids, 0.9 NaCl is considered isotonic.